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2 edition of Some studies with benzimidazoles and related heterocycles found in the catalog.

Some studies with benzimidazoles and related heterocycles

Donald Lloyd Winston Burford

Some studies with benzimidazoles and related heterocycles

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Published .
Written in English


Edition Notes

Thesis(Ph.D.) - Loughborough University of Technology.

Statementby David Lloyd Winston Burford.
ID Numbers
Open LibraryOL13930893M

Vanden, L. Laughton, C. Brake, C. Heterogeneously catalyzed C-5 bromination by functionalized silica. Zhao, M.

No metal, base, or other additives were needed. Substrates having either electron-donating or -withdrawing substituents undergo the cyclization at moderate temperature. Farag, M. Bergman, J. Christoffers, Synlett,

Kumar, Synlett,26, However, large libraries of benzimidazoles are needed in medicinal chemistry, catalysis, and materials science in order to discover fine-tuned properties and to optimize these. Xu, Synlett,29, Bastug, C. This method features mild conditions, short reaction times, high yields, and a simple procedure.


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Some studies with benzimidazoles and related heterocycles by Donald Lloyd Winston Burford Download PDF Ebook

Benzimidazoles are considered as an optimistic class of bioactive heterocyclic compounds that possesses a range of biological activities.

Benzimidazole Derivatives as Potential Antimicrobial and Antiulcer Agents: A Mini Review

Zhou, R. Even more powerful methods are anticipated to emerge in this area to make these positions also available Some studies with benzimidazoles and related heterocycles book selective late-stage functionalization through direct C—H activation.

Progress in Heterocyclic Chemistry. Synthesis and biological activity of 2- trifluoromethyl -iH-benzimidazole derivative against some protozoa and trichinella, spiral. Tidwell, C. Figure 3. Kargbo, Z. Synthesis,Characterisation and Antibacterial evaluation of some potent 2- substituted benzimidazoles Analogs.

Synthesis, characterization of some novel benzimidazole derivatives of 1-Bromo-2,4dinitrobenzene and their antifungal activities. Cu-catalyzed N-arylation. A selectivity issue must be mentioned for unsymmetrical benzimidazoles with a free N—H.

Plaskon, D. Methods: Benzimidazole derivatives are synthesized by reaction between orthophenylene diamine and anthranillic acid followed by acetylation in the presence of acetic anhydride. Hitchings, Tetrahedron,47, G Alvarez. A practical intramolecular C-H amidation methodology using molecular iodine under basic conditions enables a transition-metal-free cyclization of crude imines for the sequential synthesis of N-protected benzimidazoles without purification of less stable condensation intermediates.

Bao, J. A more powerful strategy would be to start with available benzimidazoles and be able to do functionalization with desired groups directly onto the scaffold—so-called late-stage functionalization [ 5 ].

Dennis, Chem.Benzimidazole is the heterocyclic compound formed by the fusion of benzene and imidazole ring. Benzimidazole analogs are of great significant because of their various clinical applications and biological activity. Benzimidazoles are considered as an optimistic class of bioactive heterocyclic compounds that possesses a range of biological.

Nov 12,  · Benzimidazoles and related heterocycles. A novel acid-catalyzed rearrangement in the system 3-benzoylquinoxalin-2(1H)-one-aldehyde-ammonium acetate as a simple and efficient route to 2-(imidazolyl)benzimidazoles. V. A. Mamedov 1,Cited by: 3.

Jan 04,  · Benzimidazoles and related heterocycles. 8.

Isotonitazene

Acid-catalyzed rearrangement of 3-aryl-1’H-spiro[2-pyrazoline-5,2’-quinoxalin]-3’(4’H)-ones as a new efficient method for the synthesis of 2-(pyrazolyl)benzimidazoles benzimidazoles. Possible mechanisms of this rearrangement are considered.

Cited by: The combination of two or more biologically important azole scaffolds could pdf a pdf class of azole based antifungal agents. To this end, we designed some hybrid compounds bearing benzimidazole and 1,3,4-oxadiazole rings based upon the studies that reported the antifungal potentials of such compounds [20,21,22,23].

The electron rich Cited by: 5.Buy Benzimidazoles and Cogeneric Tricyclic Compounds, Part 1 (Chemistry of Heterocyclic Compounds: A Series Of Monographs) on tjarrodbonta.com FREE SHIPPING on qualified ordersAuthor: P. N. Preston.Buy Benzimidazoles and Ebook Tricyclic Compounds, Part 1 (Chemistry of Heterocyclic Compounds: A Series Of Monographs) on tjarrodbonta.com FREE SHIPPING on qualified ordersAuthor: P.

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